Gavin: Sorry, you must have the wrong number what is topamax 100 mg used for "The majority of the risk of heart disease can be attributed to lifestyle factors, such as smoking, lack of exercise, poor diet, diabetes, high blood pressure and high cholesterol," Pande said. "The good news is that these are modifiable risk factors, which means that they are factors that you have the power to change. If you smoke, you can quit. If you don't exercise, you can get more active. If you have diabetes or high blood pressure or high cholesterol, you can talk to your doctor and get these treated."