Luis: Could I have , please? cost of levaquin 750 mg Dr. Ryan Stone (Sandra Bullock) and Matt Kowalski (George Clooney) are astronauts whose routine space mission has been interrupted by a perfect storm of satellite debris. What results is a Murphy's Law scenario in the high stakes game of space exploration. The final frontier is a jungle, to say the least, and one degree of difference could send them hurtling to the stars forever.